Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690441 | 0.87 | MAPT (0.47) | ALDH1A1GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL3227920 | 0.82 | POLB (0.49) | ALDH1A1GAAALOX5KMT2AMEN1 | |
| SCHEMBL3457181 | 0.81 | ALDH1A1 (0.70) | ALDH1A1GAANR4A1KMT2AMEN1 | |
| SCHEMBL3227905 | 0.78 | ALDH1A1 (0.52) | ALDH1A1GAAALOX5KMT2AMEN1 | |
| SCHEMBL11747645 | 0.77 | KMT2A (0.41) | ALDH1A1GAAALOX5NR4A1KMT2A | |
| SCHEMBL908271 | 0.76 | ABL1 (0.59) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6367851 | 0.75 | MAPT (0.51) | GAAKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL31594790 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAALOX5KMT2AMEN1 | |
| SCHEMBL1008089 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAALOX5KMT2AMEN1 | |
| SCHEMBL11217956 | 0.75 | ALOX5 (0.52) | ALDH1A1GAAALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003927-A | DIURETICS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |