Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427006 | 0.88 | KMT2A (0.39) | KDM5AKDM4CDNM1KDM4ECYP2C19 | |
| SCHEMBL15146684 | 0.82 | KDM4E (0.46) | KDM5AKDM4CDNM1KDM4EALDH1A1 | |
| SCHEMBL11442556 | 0.80 | MEN1 (0.54) | KDM5AKDM4CDNM1KDM4ECYP2D6 | |
| SCHEMBL25204410 | 0.80 | MAPT (0.35) | KDM5ADNM1KDM4ECYP2C19CYP2D6 | |
| SCHEMBL2835194 | 0.79 | ALDH1A1 (0.49) | KDM4ECYP2C19CYP2D6ALDH1A1SIGMAR1 | |
| SCHEMBL1583774 | 0.78 | CARM1 (0.34) | DNM1KDM4ECYP2C19CYP2D6TMEM97 | |
| SCHEMBL1414877 | 0.78 | — | — | |
| SCHEMBL16479251 | 0.77 | DNM1 (0.53) | KDM5AKDM4CDNM1ALDH1A1LMNA | |
| SCHEMBL19400553 | 0.77 | POLB (0.39) | KDM5AKDM4CDNM1KDM4EALDH1A1 | |
| SCHEMBL13646072 | 0.77 | TSHR (0.43) | KDM5AKDM4CDNM1KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024019936-A1 | NANOMATERIALS COMPRISING TRIOLS | BEAM THERAPEUTICS INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-4281050-A1 | NANOMATERIALS | Beam Therapeutics Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| US-4026831-A | ADHESIVES, PAINT RESINS, ELECTROSTATIC INHIBITORS, RUST INHIBITORS | MIYOSHI YUSHI KABUSHIKI KAISHA (JA) | 1977-05-31 | — | — | US | disclosed |