SCHEMBL1171

SCHEMBL1171

O=C(OO)c1ccccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.60
CES1 P23141 1/20 0.60
ALDH1A1 P00352 2/20 0.58
POLB P06746 2/20 0.54
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
HPGD P15428 4/20 0.51
RAB9A P51151 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
PKM P14618 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
NPC1 O15118 1/20 0.51
GAA P10253 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508856 1.00 CES2 (0.60) CES2CES1ALDH1A1POLBESR1
Ammonia Solution, Strong SCHEMBL28212326 0.98 CES2 (0.58) CES2CES1ALDH1A1POLBESR1
SCHEMBL27398420 0.98 CES2 (0.58) CES2CES1ALDH1A1POLBESR1
Methylene Chloride SCHEMBL7691952 0.94 CES2 (0.54) CES2CES1ALDH1A1POLBESR1
SCHEMBL4669070 0.89 CES2 (0.48) CES2CES1ALDH1A1POLBESR1
Tert-Butyl Hydroperoxide SCHEMBL27877573 0.89 CES2 (0.48) CES2CES1ALDH1A1POLBESR1
Toluene SCHEMBL28292440 0.89 ALDH1A1 (0.52) CES2CES1ALDH1A1POLBESR1
Ether SCHEMBL27526093 0.87 TSHR (0.47) CES2CES1ALDH1A1POLBESR1
SCHEMBL2153551 0.84 CES2 (0.62) CES2CES1ALDH1A1POLBESR1
SCHEMBL36252 0.84 CES2 (0.62) CES2CES1ALDH1A1POLBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7944 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462412-B C11a-OH tetracycline compound and synthesis method thereof 盐城市大丰区天生联合药业有限公司 2026-05-12 CN claimed
EP-4723887-A1 METHODS AND COMPOUNDS University of Leicester (GB) 2026-04-15 EP claimed
EP-4642788-A1 CHEMICAL SYNTHESIS METHODS AND CDDO/CDDO-EA PREPARATIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-05 EP claimed
WO-2025124404-A1 BISAMIDE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-06-19 WO claimed
CN-120118288-A Siloxane bridged protocatechuic acid-based epoxy resin and synthetic method and application thereof 中国科学院天津工业生物技术研究所 2025-06-10 CN claimed
CN-119931783-A Laundry detergent containing biological enzyme and preparation method thereof 河南贞仕洁生物科技有限公司 2025-05-06 CN claimed
WO-2025059261-A1 PIPERAZINYL AND MORPHOLINO HYDROXYLAMINES AND METHODS FOR MAKING THE SAME UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2025-03-20 WO claimed
CN-119638614-A Recycling method of waste liquid generated in production of avibactam intermediate 德州宏海医药科技有限公司 2025-03-18 CN claimed
WO-2024252135-A1 METHODS AND COMPOUNDS UNIVERSITY OF LEICESTER (GB) 2024-12-12 WO claimed
CN-118994849-A Low-chroma epoxy resin and production process thereof 周超 2024-11-22 CN claimed
EP-0330329-A1 Antiulcer pyrimidine derivatives PFIZER INC. (US) 1989-08-30 EP claimed
EP-0159823-B1 PREPARATION OF 14-HYDROXY-N-ETHOXY-CARBONYL-NORCODEINONE Mallinckrodt, Inc. (a Delaware corporation) (US) 1989-08-09 EP claimed
US-4731456-A Process for the preparation of clausenamide BAYER AKTIENGESELLSCHAFT (DE) 1988-03-15 US claimed
US-4731455-A Process for the preparation of gamma-butyrolactams BAYER AKTIENGESELLSCHAFT (DE) 1988-03-15 US claimed
US-4639520-A Preparation of 14-hydroxy-N-ethoxy-carbonyl-norcodeinone MALLINCKRODT, INC. (US) 1987-01-27 US claimed
EP-0186803-A2 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions NEOPHARMED S.p.A. (IT) 1986-07-09 EP claimed
CN-85107830-A The imidazoles that replaces and the preparation method of triazole 1986-07-02 CN claimed
EP-0159823-A1 Preparation of 14-Hydroxy-N-Ethoxy-Carbonyl-Norcodeinone Mallinckrodt, Inc. (a Delaware corporation) (US) 1985-10-30 EP claimed
EP-0061109-B1 ADHESIVES AND SEALANTS Henkel Kommanditgesellschaft auf Aktien (DE) 1985-04-17 EP claimed
US-4059595-A Process for preparing 3-oxy-4H-pyran-4-one derivatives OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHI (JA) 1977-11-22 US claimed