Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684013 | 0.89 | DNMT3A (0.65) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11705608 | 0.85 | TAAR1 (0.73) | NPC1RAB9ADNMT3AADORA2AADORA2B | |
| SCHEMBL11683949 | 0.83 | KDM4E (0.58) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30686690 | 0.80 | HPGD (0.78) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26936103 | 0.80 | HPGD (0.78) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5321712 | 0.80 | DNMT3A (0.69) | NPC1RAB9ASMN1; SMN2DNMT3AADORA2A | |
| SCHEMBL11708524 | 0.80 | ALDH1A1 (0.48) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26936102 | 0.79 | HPGD (0.86) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11706215 | 0.79 | ALDH1A1 (0.65) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26922278 | 0.78 | HPGD (0.84) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |