Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.73 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684013 | 0.86 | DNMT3A (0.65) | TAAR1DNMT3AADORA2AADORA2BNPC1 | |
| SCHEMBL11711213 | 0.85 | HPGD (0.60) | TAAR1DNMT3AADORA2AADORA2BCNR2 | |
| SCHEMBL11708595 | 0.80 | RAB9A (0.73) | DNMT3ACNR2NPC1RAB9A | |
| SCHEMBL5321712 | 0.79 | DNMT3A (0.69) | TAAR1DNMT3AADORA2AADORA2BNPC1 | |
| SCHEMBL11707327 | 0.79 | RAB9A (0.59) | CNR2KDM4ENPC1RAB9A | |
| SCHEMBL11708512 | 0.78 | TAAR1 (0.57) | TAAR1KDM4EPOLB | |
| SCHEMBL11706215 | 0.78 | ALDH1A1 (0.65) | DNMT3AADORA2AADORA2BNPC1RAB9A | |
| SCHEMBL11706684 | 0.77 | RAB9A (0.65) | KDM4ENPC1RAB9AESRRBESRRG | |
| SCHEMBL11687781 | 0.77 | DNMT3A (0.93) | DNMT3A | |
| SCHEMBL11706993 | 0.76 | POLB (0.59) | DNMT3ACNR2KDM4EF13A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |