Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 4/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630673 | 0.90 | PDE5A (0.47) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11628709 | 0.86 | KDM4E (0.51) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7940546 | 0.83 | GUSB (0.58) | PDE5AGUSB | |
| SCHEMBL9295923 | 0.81 | PDE5A (0.57) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11711629 | 0.80 | GAA (0.45) | KDM6BKDM4AKDM4DHIF1ANKDM2A | |
| SCHEMBL11710197 | 0.80 | PDE5A (0.54) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11626668 | 0.80 | PDE5A (0.49) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11707410 | 0.80 | PDE5A (0.47) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL238499 | 0.80 | PTGER1 (0.47) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11666115 | 0.79 | IDO1 (0.51) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |