Idrocilamide

Idrocilamide

SCHEMBL1171237

O=C(C=Cc1ccccc1)NCCO

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.77
MMP1 P03956 3/20 0.71
MMP2 P08253 3/20 0.71
MMP9 P14780 3/20 0.71
POLB P06746 1/20 0.71
RECQL P46063 1/20 0.71
RAB9A P51151 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
EGFR P00533 1/20 0.65
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 1/20 0.61
NPC1 O15118 1/20 0.61
HDAC7 Q8WUI4 1/20 0.61
HDAC10 Q969S8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Idrocilamide SCHEMBL1171234 1.00 KMT2A (0.77) KMT2AMMP1MMP2MMP9POLB
SCHEMBL11590847 0.91 KMT2A (0.86) KMT2AMMP1MMP2MMP9POLB
SCHEMBL27093064 0.90 KMT2A (0.84) KMT2AMMP1MMP2MMP9POLB
SCHEMBL27093051 0.90 KMT2A (0.84) KMT2AMMP1MMP2MMP9POLB
SCHEMBL1193088 0.88 KMT2A (0.81) KMT2AMMP1MMP2MMP9POLB
SCHEMBL27093061 0.88 KMT2A (0.81) KMT2AMMP1MMP2MMP9POLB
SCHEMBL25193280 0.87 KMT2A (1.00) KMT2AMMP1MMP2MMP9POLB
SCHEMBL3208177 0.87 KMT2A (0.93) KMT2AMMP1MMP2MMP9POLB
SCHEMBL27093047 0.87 KMT2A (0.79) KMT2AMMP1MMP2MMP9POLB
SCHEMBL27093034 0.87 KMT2A (0.79) KMT2AMMP1MMP2MMP9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025068949-A1 EMRUSOLMIN FOR USE IN TREATING MULTIPLE SYSTEM ATROPHY TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2025-04-03 WO claimed
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
US-20220151955-A1 KETAMINE FOR THE TREATMENT OF POSTPARTUM SYMPTOMS AND DISORDERS THE KETAMINE RESEARCH FOUNDATION 2022-05-19 US claimed
EP-3923920-A1 KETAMINE FOR THE TREATMENT OF POSTPARTUM SYMPTOMS AND DISORDERS The Ketamine Research Foundation (US) 2021-12-22 EP claimed
CN-112898816-B Photosensitive leveling wetting dispersant for optical fiber coloring ink and preparation method and application thereof 武汉长盈鑫科技有限公司 2021-11-16 CN claimed
CN-112898816-A Photosensitive leveling wetting dispersant for optical fiber coloring ink and preparation method and application thereof 武汉长盈鑫科技有限公司 2021-06-04 CN claimed
US-20210113493-A1 KETAMINE FOR THE TREATMENT OF MENSTRUALLY RELATED SYMPTOMS WOLFSON PHILIP E (US) 2021-04-22 US claimed
WO-2021026232-A1 KETAMINE FOR THE TREATMENT OF POSTPARTUM SYMPTOMS AND DISORDERS THE KETAMINE RESEARCH FOUNDATION (US) 2021-02-11 WO claimed
EP-3548014-A1 KETAMINE FOR THE TREATMENT OF MENSTRUALLY RELATED SYMPTOMS Wolfson, Philip, E. (US) 2019-10-09 EP claimed
WO-2018102488-A1 KETAMINE FOR THE TREATMENT OF MENSTRUALLY RELATED SYMPTOMS WOLFSON PHILIP E (US) 2018-06-07 WO claimed
US-20050008702-A1 Rupturing controlled release device having a preformed passageway Osmotica Kereskedelmi és Szolgáltató KFT (HU) 2005-01-13 US claimed
WO-2004112723-A2 TROPICAL THERAPY FOR THE TREATMENT OF MIGRAINES, MUSCLE SPRAINS, MUSCLE SPASM, SPASTICITY AND RELATED CONDITIONS AUNG-DIN RONALD (US) 2004-12-29 WO claimed
US-20040204413-A1 Pharmaceutical compositions containing a COX-II inhibitor and a muscle relaxant OSMOTICA CORP. (VG) 2004-10-14 US claimed
EP-1362585-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING A COX-II INHIBITOR AND A MUSCLE RELAXANT Osmotica Corp. (VG) 2003-11-19 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0341745-B1 Crosslinked carboxy polysaccharides FIDIA SPA (IT) 1994-12-14 EP claimed
EP-0094283-B1 SUSTAINED-RELEASE THEOPHYLLIN DRUG FORMULATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-11-21 EP claimed
US-4512994-A ANTIASTHMATIC AGENTS;BRONCHO DILATORS LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-04-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151955-A1 KETAMINE FOR THE TREATMENT OF POSTPARTUM SYMPTOMS AND DISORDERS OXTR, PNISR, KCNQ5 KMT2A 228/4885MMP1 4066/4885MMP2 3594/4885
US-20210113493-A1 KETAMINE FOR THE TREATMENT OF MENSTRUALLY RELATED SYMPTOMS KCNK5, KCNQ5, KCND2 KMT2A 143/4885MMP1 4382/4885MMP2 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.