Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930701 | 0.83 | DRD2 (0.59) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL6258542 | 0.81 | DRD2 (0.68) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL4484524 | 0.79 | DRD2 (0.56) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL5857455 | 0.79 | ATM (0.57) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL10796236 | 0.77 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL6833922 | 0.77 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL651852 | 0.77 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL3979738 | 0.77 | CYP2D6 (0.58) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL2066381 | 0.77 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL11241586 | 0.77 | ATM (0.41) | ATMDRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053477-A | 5-(1,1-DIPHENYL-3-(4-PHENYLPIPERIDINO)PROPYL)-2-METHYL-1,3,4-OXADIAZOLE AND RELATED COMPOUNDS | G. D. SEARLE & CO. (US) | 1977-10-11 | — | — | US | disclosed |