SCHEMBL930701

SCHEMBL930701

N#CC(CCBr)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.59
DRD4 P21917 2/20 0.59
OPRM1 P35372 2/20 0.59
DRD3 P35462 2/20 0.59
CYP2D6 P10635 2/20 0.59
KCNA3 P22001 8/20 0.53
ATM Q13315 1/20 0.52
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CCR3 P51677 2/20 0.46
CHRM2 P08172 2/20 0.41
CHRM1 P11229 2/20 0.41
CHRM3 P20309 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
CCR1 P32246 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626646 0.89 DRD2 (0.50) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL4484524 0.88 DRD2 (0.56) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL6258542 0.87 DRD2 (0.68) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL11625942 0.85 CCR1 (0.47) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL11712752 0.83 ATM (0.55) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL18015780 0.80 DRD2 (0.61) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL7090276 0.80 DRD2 (0.40) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL12440029 0.79 DRD2 (0.59) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL1341963 0.79 DRD2 (0.59) DRD2DRD4OPRM1DRD3CYP2D6
SCHEMBL4014770 0.79 DRD2 (0.65) DRD2DRD4OPRM1DRD3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375030-B Preparation method of diphenoxylate hydrochloride 常州康普药业有限公司 2023-02-03 CN claimed
CN-112375030-A Preparation method of diphenoxylate hydrochloride 常州康普药业有限公司 2021-02-19 CN claimed
CN-104614468-B Method for separating imidafenacin and related substances thereof by high performance liquid chromatography 北京万全德众医药生物技术有限公司 2020-11-03 CN claimed
EP-2354133-B1 Method for producing 1-(3-Cyano-3,3-diphenylpropyl)-4-(1-piperidyl)-piperidine-4-carboxamide (Piritramide) HAMELN RDS GMBH (DE) 2013-12-11 EP claimed
EP-2354133-A1 Method for producing 1-(3-Cyano-3,3-diphenylpropyl)-4-(1-piperidyl)-piperidine-4-carboxamide (Piritramide) hameln rds gmbh (DE) 2011-08-10 EP claimed
US-4086234-A Process for the preparation of tertiary amines G. D. SEARLE & CO. (US) 1978-04-25 US claimed
JP-11100366-A None JP disclosed
US-12631983-B2 Silica particle, toner for developing electrostatic charge image, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method FUJIFILM BUSINESS INNOVATION CORP. (JP) 2026-05-19 US disclosed
CN-115124043-B Silica particles and method for producing same 富士胶片商业创新有限公司 2026-05-12 CN disclosed
US-12535752-B2 Electrostatic charge image developing toner, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method FUJIFILM BUSINESS INNOVATION CORP. (JP) 2026-01-27 US disclosed
US-12455515-B2 Electrostatic charge image developing toner, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-10-28 US disclosed
EP-4250015-B1 ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, ELECTROSTATIC CHARGE IMAGE DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD FUJIFILM BUSINESS INNOVATION CORP (JP) 2025-10-08 EP disclosed
US-12421396-B2 Silica particles and method for producing the same FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-09-23 US disclosed
US-4308249-A Radiopharmaceutical complexes of N-(tri-substituted alkyl)-iminodiacetic acids G. D. SEARLE & CO. (US) 1981-12-29 US disclosed
US-4086234-A Process for the preparation of tertiary amines G. D. SEARLE & CO. (US) 1978-04-25 US disclosed
US-RE29556-E 1,1-Diaryl-1-oxadiazol-alkylamines G. D. SEARLE & CO. (US) 1978-02-28 US disclosed
US-4053477-A 5-(1,1-DIPHENYL-3-(4-PHENYLPIPERIDINO)PROPYL)-2-METHYL-1,3,4-OXADIAZOLE AND RELATED COMPOUNDS G. D. SEARLE & CO. (US) 1977-10-11 US disclosed
US-4017491-A 1,1-Diaryl-1H-tetrazole amines G. D. SEARLE & CO. (US) 1977-04-12 US disclosed
US-4013668-A 5-(1,1-DIPHENYL-3-(5- OR 6-HYDROXY-2-AZABICYCLO(2.2.2)OCT-2-YL)PROPYL)-2-ALKYL-1,3,4-OXADIAZOLES AND RELATED COMPOUNDS G. D. SEARLE & CO. (US) 1977-03-22 US disclosed
US-4003904-A Anti-diarrheal oxadiazoles G. D. SEARLE & CO. (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631983-B2 Silica particle, toner for developing electrostatic charge image, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method BET1, SMARCC1, SMARCC2 DRD2 3882/4885DRD4 4187/4885OPRM1 4224/4885
US-12535752-B2 Electrostatic charge image developing toner, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method H1-2, H1-0, CECR2 DRD2 3623/4885DRD4 3809/4885OPRM1 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.