Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753851 | 0.86 | KMT2A (0.56) | KMT2AHSD17B14CES2CES1HDAC3 | |
| SCHEMBL6771181 | 0.86 | HSD17B14 (0.71) | KMT2AHSD17B14CES2CES1HDAC3 | |
| SCHEMBL11715543 | 0.81 | LMNA (0.56) | KMT2AHSD17B14L3MBTL1LMNAALDH1A1 | |
| SCHEMBL8866141 | 0.81 | KMT2A (0.72) | KMT2AHSD17B14CES2CES1HDAC3 | |
| SCHEMBL10688592 | 0.80 | KMT2A (0.66) | KMT2AHSD17B14CES2CES1HDAC3 | |
| SCHEMBL7266631 | 0.78 | KMT2A (0.62) | KMT2AHSD17B14CES2CES1L3MBTL1 | |
| SCHEMBL6947603 | 0.78 | HSD17B14 (0.74) | KMT2AHSD17B14CES2CES1HDAC1 | |
| SCHEMBL11869288 | 0.78 | KMT2A (0.50) | KMT2AHSD17B14HDAC1HDAC8HDAC6 | |
| SCHEMBL3836387 | 0.77 | KMT2A (0.61) | KMT2AHSD17B14CES2CES1L3MBTL1 | |
| SCHEMBL29373829 | 0.76 | KMT2A (1.00) | KMT2AHSD17B14CES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026936-A | Anthelmintic pyridine and thiazole substituted benzimidazole carbamates | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |