Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120145 | 0.83 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2121576 | 0.81 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2119875 | 0.81 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2119250 | 0.81 | MEN1 (1.00) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL2117559 | 0.80 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11596061 | 0.80 | KMT2A (0.70) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2119498 | 0.78 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3883351 | 0.78 | MRGPRX4 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL1614968 | 0.77 | TAS2R14 (0.72) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11715431 | 0.77 | MEN1 (0.50) | KMT2AMEN1ALDH1A1POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029787-A | Basically substituted 3-sulfamoylbenzoic acid derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |