Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713106 | 1.00 | MEN1 (0.41) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27792891 | 1.00 | MEN1 (0.41) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL1871186 | 1.00 | MEN1 (0.41) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28511142 | 0.84 | MEN1 (0.38) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL20505646 | 0.81 | KMT2A (0.49) | MEN1LMNAMAPTKMT2AL3MBTL1 | |
| SCHEMBL3283090 | 0.78 | IDO1 (0.39) | MEN1MAPTKMT2AGAATDP1 | |
| SCHEMBL29018563 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL1279017 | 0.78 | NR5A1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL3103832 | 0.78 | NR5A1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL5133914 | 0.78 | NR5A1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011334-A | USE OF SUBSTITUTED FURAN AND THIOPHENE CARBOXALDEHYDES AS HYPOLIPIDEMIC AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-03-08 | — | — | US | disclosed |