Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283090 | 0.82 | IDO1 (0.39) | ALDH1A1HPGDHTTSMN1; SMN2FDPS | |
| SCHEMBL11713104 | 0.78 | MEN1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL1871186 | 0.78 | MEN1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL11713106 | 0.78 | MEN1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL20505646 | 0.78 | KMT2A (0.49) | ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL28234656 | 0.74 | KEAP1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL28272400 | 0.72 | RIPK1 (0.36) | HPGD | |
| SCHEMBL28994748 | 0.71 | PDE4B (0.34) | — | |
| SCHEMBL3421374 | 0.71 | — | — | |
| SCHEMBL10305111 | 0.70 | KMT2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284040-B | Nitrogen-containing heterocyclic compound and medical application thereof | 华润医药研究院（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116284040-A | Nitrogen-containing heterocyclic compound and medical application thereof | 华润医药研究院（深圳）有限公司 | 2023-06-23 | — | — | CN | disclosed |