Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NGFR | P08138 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714206 | 0.86 | KDM4E (0.50) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL11719392 | 0.82 | GAA (0.45) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL11638566 | 0.81 | GLA (0.58) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL11723446 | 0.78 | GPR35 (0.68) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL11718229 | 0.76 | GPR35 (0.60) | NGFRKDM4ECYP1A2GPR35HPGD | |
| SCHEMBL11409016 | 0.74 | GAA (0.66) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL11807432 | 0.72 | GLA (0.68) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL9452301 | 0.71 | KDM4E (0.47) | GLAGAAKDM4ECYP1A2XDH | |
| SCHEMBL2903161 | 0.71 | GLA (0.51) | NGFRGLAGAAKDM4ECYP1A2 | |
| SCHEMBL51079 | 0.71 | GAA (0.61) | NGFRGLAGAAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064248-A | TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |