Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | NGFR | P08138 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51079 | 0.90 | GAA (0.61) | GAAGLACYP19A1NQO2CYP1A2 | |
| SCHEMBL51080 | 0.88 | GLA (0.59) | GAAGLACYP19A1NQO2CYP1A2 | |
| SCHEMBL11107211 | 0.84 | GLA (0.52) | GAAGLACYP19A1NQO2CYP1A2 | |
| SCHEMBL644452 | 0.80 | KDM4E (0.73) | GAAGLACYP1A2KDM4EHPGD | |
| SCHEMBL2476568 | 0.76 | GLA (0.52) | GAAGLAKDM4EHPGDMAPT | |
| SCHEMBL8319614 | 0.76 | GAA (0.62) | GAAGLACYP19A1NQO2CYP1A2 | |
| SCHEMBL8324363 | 0.75 | GAA (0.60) | GAAGLACYP1A2KDM4EHPGD | |
| SCHEMBL11807432 | 0.74 | GLA (0.68) | GAAGLACYP1A2KDM4EHPGD | |
| SCHEMBL11713151 | 0.74 | NGFR (0.51) | GAAGLACYP1A2KDM4EHPGD | |
| SCHEMBL5355599 | 0.74 | GLA (0.68) | GAAGLAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55151511-A | — | — | None | — | — | JP | disclosed |
| JP-S55151511-A | ANTIALLERGIC AGENT CONSISTING MAINLY OF KYNURENIC ESTER DERIVATIVE | SANKYO CO LTD | 1980-11-26 | — | — | JP | disclosed |