Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | F13A1 | P00488 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858 | 0.89 | KDM4E (0.69) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL31736052 | 0.87 | KDM4E (0.67) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL10592850 | 0.87 | KDM4E (0.84) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL11713261 | 0.86 | KDM4E (0.89) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL1728418 | 0.85 | CNR1 (0.59) | CNR1HIF1ALMNAPTGS1FFAR1 | |
| SCHEMBL7356956 | 0.84 | KDM4E (0.62) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL19692814 | 0.83 | KDM4E (0.54) | KDM4EF13A1SMN1; SMN2CNR1HIF1A | |
| SCHEMBL30259923 | 0.83 | MTNR1A (0.61) | CNR1HIF1AFFAR1MEN1KMT2A | |
| SCHEMBL4701625 | 0.83 | KDM4E (0.62) | KDM4EF13A1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL26300873 | 0.82 | PLAAT5 (0.57) | KDM4ESMN1; SMN2CNR1HIF1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | NOVARTIS AG (CH) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | DNPEP, MME, DPP7 | KDM4E 919/4885F13A1 1789/4885SMN1; SMN2 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.