Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714547 | 0.92 | NR4A1 (0.40) | NR4A1MKNK1LTA4HPRKACAPRKACG | |
| SCHEMBL11715795 | 0.86 | MKNK1 (0.38) | NR4A1MKNK1LTA4HPRKACAPRKACG | |
| SCHEMBL11715787 | 0.84 | MKNK1 (0.34) | MKNK1PRKACAPRKACGPRKACB | |
| SCHEMBL11720743 | 0.83 | HRH3 (0.37) | MKNK1 | |
| SCHEMBL11722232 | 0.80 | MKNK1 (0.33) | MKNK1 | |
| SCHEMBL11714984 | 0.79 | LTA4H (0.37) | MKNK1LTA4HKDM4E | |
| SCHEMBL11712033 | 0.78 | CHRNB4 (0.47) | NR4A1LTA4H | |
| SCHEMBL11716280 | 0.77 | LTA4H (0.50) | NR4A1LTA4H | |
| SCHEMBL11713407 | 0.76 | SLC6A2 (0.38) | NR4A1MKNK1KDM4E | |
| SCHEMBL11716570 | 0.74 | SLC6A2 (0.43) | NR4A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |