Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715787 | 0.91 | MKNK1 (0.34) | MKNK1 | |
| SCHEMBL11714547 | 0.85 | NR4A1 (0.40) | MKNK1 | |
| SCHEMBL11714562 | 0.83 | MKNK1 (0.37) | MKNK1 | |
| SCHEMBL11714984 | 0.81 | LTA4H (0.37) | MKNK1 | |
| SCHEMBL11713402 | 0.80 | NR4A1 (0.37) | MKNK1 | |
| SCHEMBL11714152 | 0.78 | CHEK2 (0.41) | — | |
| SCHEMBL11715795 | 0.77 | MKNK1 (0.38) | MKNK1 | |
| SCHEMBL11710862 | 0.77 | CHEK2 (0.45) | — | |
| SCHEMBL11722240 | 0.76 | SLC6A4 (0.35) | MKNK1 | |
| SCHEMBL11720743 | 0.74 | HRH3 (0.37) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |