Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719037 | 0.99 | NR4A1 (0.45) | NR4A1SIGMAR1ESR1ESR2DRD3 | |
| SCHEMBL11716967 | 0.91 | NR4A1 (0.42) | NR4A1SIGMAR1ESR1ESR2LTA4H | |
| SCHEMBL11715683 | 0.90 | ACE2 (0.43) | NR4A1SIGMAR1ESR1ESR2LTA4H | |
| SCHEMBL11721125 | 0.85 | LTA4H (0.41) | NR4A1SIGMAR1ESR1ESR2DRD3 | |
| SCHEMBL11717405 | 0.84 | LTA4H (0.40) | NR4A1SIGMAR1ESR1ESR2LTA4H | |
| SCHEMBL11721859 | 0.83 | SIGMAR1 (0.41) | SIGMAR1ESR1ESR2DRD3MEN1 | |
| SCHEMBL11715370 | 0.82 | SIGMAR1 (0.41) | SIGMAR1ESR1ESR2DRD3 | |
| SCHEMBL11712040 | 0.81 | ESR1 (0.53) | SIGMAR1ESR1ESR2DRD3LTA4H | |
| SCHEMBL4349235 | 0.81 | SIGMAR1 (0.51) | SIGMAR1ESR1ESR2DRD3LTA4H | |
| SCHEMBL4349237 | 0.81 | SIGMAR1 (0.51) | SIGMAR1ESR1ESR2DRD3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |