Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710065 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL538380 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL14646680 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL13804033 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL7849270 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL30789059 | 0.82 | KMT2A (0.68) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL5520356 | 0.82 | CA1 (0.58) | KMT2AMEN1MAOACA1CA2 | |
| SCHEMBL11714295 | 0.81 | KMT2A (0.67) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| Hydrochloric Acid SCHEMBL4772373 | 0.81 | KMT2A (0.97) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL17821830 | 0.79 | MEN1 (0.60) | KMT2AMEN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001244-A | 1-ARYL-3,4-DIHYDRO-2(1H)-ISOQUINOLINE CARBONYL CHLORIDES | G. D. SEARLE & CO. (US) | 1977-01-04 | — | — | US | disclosed |