Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28128145 | 0.91 | CYP2C9 (0.46) | SIGMAR1HPGDACHEGAAMEN1 | |
| SCHEMBL11710461 | 0.91 | PKM (0.47) | HPGDGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL16116721 | 0.83 | HPGD (0.55) | SIGMAR1HPGDACHEGAACHRNB2 | |
| SCHEMBL15617689 | 0.81 | HPGD (0.53) | SIGMAR1HPGDACHEGAACHRNB2 | |
| SCHEMBL1914320 | 0.79 | NAMPT (0.60) | SIGMAR1HPGDACHECHRNB2CHRNB4 | |
| SCHEMBL4818101 | 0.75 | CRBN (0.56) | SIGMAR1HPGDACHEBLMCRBN | |
| SCHEMBL4818087 | 0.75 | CRBN (0.56) | SIGMAR1HPGDACHEBLMCRBN | |
| SCHEMBL11708892 | 0.75 | POLB (0.54) | USP2ALDH1A1KDM4EALOX15 | |
| SCHEMBL11714571 | 0.75 | HPGD (0.54) | SIGMAR1HPGDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2884285 | 0.75 | KMT2A (0.56) | GAACHRNB2CHRNA7CHRNA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007156-A | ULTRAVIOLET RADIATION | CIBA-GEIGY CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |