Pyridine

Pyridine

SCHEMBL28128145

CC1(C)CN(C(=O)c2ccccc2)CC(C)(C)N1.c1ccncc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 5/20 0.46
CYP2D6 P10635 5/20 0.46
CYP2C19 P33261 5/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
LMNA P02545 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
CYP3A4 P08684 8/20 0.43
CYP1A2 P05177 4/20 0.43
USP2 O75604 4/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
ACHE P22303 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11713669 0.91 SIGMAR1 (0.51) ALDH1A1SIGMAR1USP2HPGDMAPK1
SCHEMBL11710461 0.82 PKM (0.47) ALDH1A1TSHRLMNAHPGDMEN1
Pyridine SCHEMBL28096804 0.79 KMT2A (0.49) ALDH1A1TSHRLMNAMAPK1MEN1
SCHEMBL16116721 0.76 HPGD (0.55) ALDH1A1LMNASIGMAR1USP2HPGD
SCHEMBL15617689 0.74 HPGD (0.53) ALDH1A1SIGMAR1USP2HPGDMAPK1
Pyridine SCHEMBL28123146 0.74 SIGMAR1 (0.81) CYP2C9CYP2D6CYP2C19ALDH1A1TSHR
Pyridine SCHEMBL28220406 0.73 TSHR (0.33) TSHR
Pyridine SCHEMBL28210200 0.72 TSHR (0.36) ALDH1A1TSHRLMNAGAA
SCHEMBL1914320 0.71 NAMPT (0.60) ALDH1A1TSHRSIGMAR1HPGDACHE
SCHEMBL4107014 0.70 MAPK1 (0.57) ALDH1A1TSHRLMNASIGMAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661270-A Use of hydroxybenzotriazole derivatives and/or hydroxy indazole derivatives as flame retardants for plastics and flameproof plastic moulded bodies 弗劳恩霍夫应用研究促进协会 2017-05-10 CN claimed
CN-107250238-B Light stabilization of polyolefins film, band and monofilament 巴斯夫欧洲公司 2019-08-20 CN disclosed
CN-106536613-B High-efficiency stabilizer 巴斯夫欧洲公司 2019-06-28 CN disclosed
CN-207898025-U Combination vamp and outsole for footwear product 耐克创新有限合伙公司 2018-09-25 CN disclosed
CN-105102522-B Use of organic oxoimides as flame retardants for plastics, flame-retardant plastic compositions and moldings produced therefrom 弗劳恩霍弗应用研究促进协会 2018-08-17 CN disclosed
CN-107849307-A Additive agent mixture 巴斯夫欧洲公司 2018-03-27 CN disclosed
CN-107835841-A Polymer composition with delayed crystallization behaviour, additive composition influencing crystallization behaviour, method for lowering crystallization point and use of additive composition 弗劳恩霍弗应用研究促进协会 2018-03-23 CN disclosed
CN-107250238-A Light stabilization of polyolefins film, band and monofilament 巴斯夫欧洲公司 2017-10-13 CN disclosed
CN-106536613-A High-efficiency stabilizer 巴斯夫欧洲公司 2017-03-22 CN disclosed