Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716476 | 0.97 | GHSR (0.57) | GHSR | |
| SCHEMBL11716164 | 0.97 | GHSR (0.57) | GHSR | |
| SCHEMBL11713218 | 0.89 | ALDH1A1 (0.63) | GHSR | |
| SCHEMBL11715413 | 0.85 | ALDH1A1 (0.58) | GHSR | |
| SCHEMBL11718388 | 0.85 | ALDH1A1 (0.58) | GHSR | |
| SCHEMBL11719061 | 0.85 | ALDH1A1 (0.47) | GHSR | |
| SCHEMBL11712605 | 0.85 | CA12 (0.52) | GHSR | |
| SCHEMBL11712076 | 0.83 | ALDH1A1 (0.66) | — | |
| SCHEMBL11715316 | 0.82 | ALDH1A1 (0.53) | GHSR | |
| SCHEMBL11715456 | 0.82 | ALDH1A1 (0.53) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001244-A | 1-ARYL-3,4-DIHYDRO-2(1H)-ISOQUINOLINE CARBONYL CHLORIDES | G. D. SEARLE & CO. (US) | 1977-01-04 | — | — | US | disclosed |