Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723026 | 0.76 | ALDH1A1 (0.65) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL11717621 | 0.76 | CA1 (0.46) | TSHRALDH1A1MAPK1CA1CA2 | |
| SCHEMBL27680948 | 0.75 | TSHR (0.50) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL2294141 | 0.74 | CA1 (0.40) | TSHRALDH1A1PTPN1CA1CA2 | |
| SCHEMBL1436392 | 0.71 | KCNN4 (0.52) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL146900 | 0.71 | TSHR (0.58) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL21082645 | 0.71 | TSHR (0.58) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL17288747 | 0.71 | TSHR (0.58) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL4117010 | 0.69 | ALDH1A1 (0.55) | TSHRALDH1A1PTPN1MAPK1CA1 | |
| SCHEMBL30619668 | 0.69 | TSHR (0.55) | TSHRALDH1A1PTPN1MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031119-A | LUBRICANTS, GREASES, SEALS | PONOMAREV ALEXEI IVANOVICH | 1977-06-21 | — | — | US | disclosed |