⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736624 | 0.97 | HRH3 (0.55) | — | |
| SCHEMBL246069 | 0.97 | — | — | |
| SCHEMBL737335 | 0.97 | HRH3 (0.55) | — | |
| SCHEMBL2102597 | 0.97 | HRH3 (0.55) | — | |
| SCHEMBL12504205 | 0.97 | HRH3 (0.55) | — | |
| Water SCHEMBL29029809 | 0.94 | HRH3 (0.52) | — | |
| SCHEMBL19837631 | 0.94 | HRH3 (0.52) | — | |
| SCHEMBL787670 | 0.93 | — | — | |
| SCHEMBL5087744 | 0.90 | POLB (0.46) | — | |
| SCHEMBL387453 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3784 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221577-A | 2-Phenoxyquinoline derivative, and preparation method and application thereof | 湖南中医药大学 | 2024-06-21 | — | — | CN | claimed |
| WO-2024120454-A1 | BIS-PHOSPHATIDYL AMINE COMPOUNDS CONTAINING MULTIPLE TERTIARY AMINO STRUCTURES, AND COMPOSITION AND USE THEREOF | 北京大学 | 2024-06-13 | — | — | WO | claimed |
| CN-118146262-A | Bi-phosphatidyl amide compound containing multiple tertiary amino structures, composition and application thereof | 北京大学 | 2024-06-07 | — | — | CN | claimed |
| CN-114450284-B | 6, 7-Dihydro-5H-pyrido [2,3-C ] pyridazine derivatives as BCL-XL protein inhibitors | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| EP-4003989-B1 | 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER | SERVIER LAB (FR) | 2023-12-27 | — | — | EP | claimed |
| EP-3590941-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXANE-QUINAZOLINE AND -LINKED DIOXANE-QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | claimed |
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| CN-117050043-A | 3-phenyl dibenzofuran compound and preparation method and application thereof | 中国海洋大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116693551-A | Dihydropyrazole azepine compound, pharmaceutical composition containing same and application of compound in resisting tumor | 浙江大学 | 2023-09-05 | — | — | CN | claimed |
| EP-0152910-B1 | PYRAZOLOPYRIDINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-07-12 | — | — | EP | claimed |
| EP-0142361-B1 | N-SUBSTITUTED-5-PHENYL-4,1-BENZOXAZEPIN-2(3H)-ONES HAVING THERAPEUTIC UTILITY | THE UPJOHN COMPANY (US) | 1988-05-11 | — | — | EP | claimed |
| US-4670432-A | Pyrazolopyridine derivatives useful in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1987-06-02 | — | — | US | claimed |
| US-4621089-A | Pyrazolopyridine derivatives and their use in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1986-11-04 | — | — | US | claimed |
| EP-0152910-A2 | pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | claimed |
| EP-0142361-A2 | N-substituted-5-phenyl-4,1-benzoxazepin-2(3H)-ones having therapeutic utility | THE UPJOHN COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| US-4450109-A | VASODILATION; CARDIOTONIC AGENTS; HYPOTENSIVE AGENTS | SS PHARMACEUTICAL CO., LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| US-4374846-A | N-Amino alkyl indole compounds compositions containing same, and a method of using same in therapy of disorders of gastrointestinal motility | KALI-CHEMIE PHARMA GMBH (DE) | 1983-02-22 | — | — | US | claimed |
| US-4039540-A | BACTERICIDES, ANIMAL GROWTH PROMOTERS | PFIZER INC. (US) | 1977-08-02 | — | — | US | claimed |
| US-3997538-A | BACTERICIDE | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-12-14 | — | — | US | claimed |