Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787670 | 0.97 | — | — | |
| SCHEMBL11716 | 0.90 | — | — | |
| SCHEMBL10483535 | 0.90 | ALOX15 (0.44) | POLBHRH3ALOX15ALDH1A1PKM | |
| SCHEMBL387453 | 0.90 | — | — | |
| SCHEMBL737335 | 0.88 | HRH3 (0.55) | POLBHRH3CARM1PRMT6PRMT8 | |
| SCHEMBL736624 | 0.88 | HRH3 (0.55) | POLBHRH3CARM1PRMT6PRMT8 | |
| SCHEMBL2102597 | 0.88 | HRH3 (0.55) | POLBHRH3CARM1PRMT6PRMT8 | |
| SCHEMBL246069 | 0.88 | — | — | |
| SCHEMBL12504205 | 0.88 | HRH3 (0.55) | POLBHRH3CARM1PRMT6PRMT8 | |
| SCHEMBL1786892 | 0.87 | CHKA (0.46) | POLBPRMT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993540-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS | CombinatoRx, Incorporated (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007103373-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS | COMBINATORX, INCORPORATED (US) | 2007-09-13 | — | — | WO | disclosed |