SCHEMBL737335

SCHEMBL737335

[CH2]CCN1CCCCCCC1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.55
LMNA P02545 1/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
CYP1A2 P05177 2/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SIGMAR1 Q99720 1/20 0.39
PSMB1 P20618 3/20 0.38
PSMB5 P28074 3/20 0.38
PSMB2 P49721 2/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL736624 1.00 HRH3 (0.55) HRH3LMNAALDH1A1MAPTPOLB
SCHEMBL12504205 1.00 HRH3 (0.55) HRH3LMNAALDH1A1MAPTPOLB
SCHEMBL2102597 1.00 HRH3 (0.55) HRH3LMNAALDH1A1MAPTPOLB
SCHEMBL246069 1.00
SCHEMBL19837631 0.97 HRH3 (0.52) HRH3LMNAALDH1A1MAPTPOLB
Water SCHEMBL29029809 0.97 HRH3 (0.52) HRH3LMNAALDH1A1MAPTPOLB
SCHEMBL11716 0.97
SCHEMBL787670 0.90
SCHEMBL5087744 0.88 POLB (0.46) HRH3LMNAALDH1A1MAPTPOLB
SCHEMBL387453 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110540679-B Rubber composition for tire and pneumatic tire 住友橡胶工业株式会社 2023-03-31 CN disclosed
CN-110540687-B Rubber composition for tire and pneumatic tire 住友橡胶工业株式会社 2023-03-10 CN disclosed
CN-110382609-B Studless tire 住友橡胶工业株式会社 2022-03-22 CN disclosed
CN-109071887-B Rubber composition 株式会社普利司通 2021-06-04 CN disclosed
CN-107108911-B Method for producing vulcanized rubber composition, and studless tire using same 住友橡胶工业株式会社 2020-11-10 CN disclosed
CN-111372985-A Spike-free antiskid tread rubber composition for winter tire 住友橡胶工业株式会社 2020-07-03 CN disclosed
CN-106987038-B Tyre for vehicle wheels 住友橡胶工业株式会社 2020-05-08 CN disclosed
CN-110540687-A Rubber composition for tire and pneumatic tire SUMITOMO RUBBER IND 2019-12-06 CN disclosed
CN-110540679-A Rubber composition for tire and pneumatic tire SUMITOMO RUBBER IND 2019-12-06 CN disclosed
EP-3080167-A2 METHOD FOR PRODUCING POLYMERIC COMPOSITIONS INCLUDING FUNCTIONALIZED POLYMERS Firestone Polymers, LLC (US) 2016-10-19 EP disclosed
US-20090209562-A1 Fused ring 4-oxopyrimidine derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-08-20 US disclosed
US-20090137576-A1 Novel Piperidine Derivative MSD K.K. (JP) 2009-05-28 US disclosed
US-7521455-B2 Fused ring 4-oxopyrimidine derivative BANYU PHARMACEUTICAL CO. LTD. (JP) 2009-04-21 US disclosed
US-20080275069-A1 Quinazoline Derivative MSD K.K. (JP) 2008-11-06 US disclosed
EP-1944301-A1 NOVEL BENZOXATHIIN DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2008-07-16 EP disclosed
EP-1892241-A1 NOVEL PIPERIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2008-02-27 EP disclosed
US-20070167453-A1 Nitrogenous fused heteroaromatic ring derivative MSD K.K. (JP) 2007-07-19 US disclosed
EP-1757594-A1 QUINAZOLINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-02-28 EP disclosed
EP-1717230-A1 FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-11-02 EP disclosed
US-20050182045-A1 Fused ring 4-oxopyrimidine derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137576-A1 Novel Piperidine Derivative HRH4, HRH3, HRH1 HRH3 2/4885LMNA 4494/4885ALDH1A1 1242/4885
US-20080275069-A1 Quinazoline Derivative HRH3, HRH4, HRH2 HRH3 1/4885LMNA 4491/4885ALDH1A1 2782/4885
US-20050182045-A1 Fused ring 4-oxopyrimidine derivative HRH4, HRH2, HRH3 HRH3 3/4885LMNA 4856/4885ALDH1A1 1717/4885
US-20090209562-A1 Fused ring 4-oxopyrimidine derivative HRH4, HRH2, HRH3 HRH3 3/4885LMNA 4856/4885ALDH1A1 1717/4885
US-20070167453-A1 Nitrogenous fused heteroaromatic ring derivative HRH3, HRH2, HRH4 HRH3 1/4885LMNA 4522/4885ALDH1A1 1934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.