Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615129 | 0.79 | LMNA (0.64) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL26768570 | 0.78 | MAOB (0.79) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL30629188 | 0.78 | MAOB (0.79) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7105478 | 0.76 | XDH (0.53) | MAOAMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28331280 | 0.75 | MAOB (0.64) | MAOBMAOACA12RAB9AACHE | |
| SCHEMBL7245118 | 0.75 | NPC1 (0.51) | MAOBMAOAMAPTKDM4EMEN1 | |
| SCHEMBL9350122 | 0.75 | MAOB (0.72) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL30629178 | 0.74 | MAOB (1.00) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL483639 | 0.74 | MAPT (0.96) | MAOACA12CA1MAPTKDM4E | |
| SCHEMBL31261599 | 0.74 | MAPT (0.96) | MAOACA12CA1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048151-A | AZO DYES, NITROGEN HETEROCYCLES, POLYMERS | SANDOZ LTD. (CH) | 1977-09-13 | — | — | US | disclosed |