Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170639 | 0.80 | SLC5A2 (0.78) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| SCHEMBL23241767 | 0.80 | SLC5A2 (0.68) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| SCHEMBL2495164 | 0.78 | SLC5A2 (0.64) | SLC5A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL17761715 | 0.78 | TP53 (0.65) | SLC5A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11713502 | 0.78 | LMNA (0.52) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| SCHEMBL11712251 | 0.76 | LMNA (0.67) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| Bromide SCHEMBL11709807 | 0.74 | LMNA (0.69) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| SCHEMBL2496996 | 0.73 | MAPT (0.60) | SLC5A2ALDH1A1CXCR3LMNASMN1; SMN2 | |
| SCHEMBL11712432 | 0.73 | NOD1 (0.72) | KMT2ATSHRHTTTP53 | |
| SCHEMBL11710220 | 0.72 | TP53 (0.51) | SLC5A2ALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004016-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |