SCHEMBL1171679

SCHEMBL1171679

S=CNC1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15855910 1.00 ADH1B (0.55)
SCHEMBL3250848 0.97
SCHEMBL12652148 0.91
SCHEMBL3237709 0.84
SCHEMBL28465622 0.75 ADH1B (0.60)
SCHEMBL6072132 0.72
SCHEMBL27458953 0.71
SCHEMBL22988657 0.71 ADH1B (1.00)
SCHEMBL2112448 0.71 ADH1B (1.00)
Cyclohexylformamide SCHEMBL26146 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110046368-A1 LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF IVASHCHENKO ANDREY ALEXANDROVICH 2011-02-24 US claimed
EP-2184064-A2 LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF Alla Chem, LLC. (US) 2010-05-12 EP claimed
US-5266707-A Anticholesterol FUJIREBIO INC. (JP) 1993-11-30 US claimed
EP-0539709-A1 3,5-Dihydroxyheptanoic acid derivatives and lactones thereof as HMG-CoA reductase inhibitors FUJIREBIO Inc. (JP) 1993-05-05 EP claimed
EP-3632441-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND DAY ONE BIOPHARMACEUTICALS INC (US) 2024-07-17 EP disclosed
CN-118344346-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-16 CN disclosed
EP-3782986-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2024-07-10 EP disclosed
CN-118290408-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-05 CN disclosed
US-20240217957-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-04 US disclosed
CN-118271298-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-02 CN disclosed
CN-118271297-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-02 CN disclosed
US-12024505-B2 Heterocyclic compounds useful as modulators of acetylcholine receptors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-02 US disclosed
US-5043372-A Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) ATOCHEM NORTH AMERICA, INC. (US) 1991-08-27 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0434079-A1 N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 EP disclosed
US-4038218-A SPRAY DRYING KAO SOAP CO., LTD. (JA) 1977-07-26 US disclosed
US-3935311-A Substitute pyridinol-containing compositions and methods for the treatment of coccidiosis SANKYO COMPANY LIMITED (JA) 1976-01-27 US disclosed