Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 13/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718420 | 0.92 | CYP1B1 (0.60) | CYP1B1ALDH1A1POLBRXFP1HDAC1 | |
| SCHEMBL11711675 | 0.85 | KMT2A (0.54) | CYP1B1ALDH1A1POLBHDAC1HDAC6 | |
| SCHEMBL11708227 | 0.85 | L3MBTL1 (0.64) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL11713364 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBHDAC1HDAC6KDM4E | |
| SCHEMBL28411749 | 0.82 | KDM4E (0.53) | CYP1B1ALDH1A1HDAC1HDAC6KDM4E | |
| SCHEMBL29053318 | 0.81 | CYP1B1 (0.63) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL11712409 | 0.81 | CYP1B1 (0.53) | CYP1B1ALDH1A1POLBRXFP1HDAC1 | |
| SCHEMBL11713257 | 0.81 | CYP1B1 (0.52) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL11712197 | 0.81 | CYP1B1 (0.50) | CYP1B1ALDH1A1POLBRXFP1HDAC1 | |
| SCHEMBL10137923 | 0.80 | CYP1B1 (0.51) | CYP1B1ALDH1A1POLBRXFP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |