Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clofibric Acid SCHEMBL11733624 | 0.84 | PPARA (0.62) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL11641659 | 0.82 | PPARA (0.72) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL11718676 | 0.80 | CYP1A2 (0.49) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL3090302 | 0.78 | PPARA (0.53) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL3091124 | 0.75 | PPARA (0.50) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| Clofibrate SCHEMBL28086141 | 0.74 | PPARA (0.94) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| Simfibrate SCHEMBL27667 | 0.73 | PPARA (0.74) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL11640865 | 0.71 | PPARA (0.72) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| Clofibrate SCHEMBL3953607 | 0.71 | PPARA (1.00) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| Clofibrate SCHEMBL2356 | 0.71 | PPARA (1.00) | PPARACYP1A2CYP3A4TSHRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017502-A | Process for purifying the mixed ester, ethylene glycol 1-(2-p-chlorophenoxy)-2-methylpropionate nicotinate | ALTER, S.A. (ES) | 1977-04-12 | — | — | US | disclosed |