Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718001 | 0.80 | PPARA (0.53) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| SCHEMBL11641659 | 0.78 | PPARA (0.72) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Nicofibrate SCHEMBL49182 | 0.71 | CYP1A2 (0.58) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Etofibrate SCHEMBL29801484 | 0.71 | L3MBTL1 (0.55) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Etofibrate SCHEMBL8168409 | 0.71 | L3MBTL1 (0.55) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Etofibrate SCHEMBL3122 | 0.71 | L3MBTL1 (0.55) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| SCHEMBL3090302 | 0.70 | PPARA (0.53) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Etofibrate SCHEMBL1649349 | 0.70 | L3MBTL1 (0.54) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| SCHEMBL11029490 | 0.70 | PPARA (0.51) | CYP1A2CYP3A4PPARATSHRABCB11 | |
| Ronifibrate SCHEMBL48852 | 0.69 | L3MBTL1 (0.59) | CYP1A2CYP3A4PPARATSHRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017502-A | Process for purifying the mixed ester, ethylene glycol 1-(2-p-chlorophenoxy)-2-methylpropionate nicotinate | ALTER, S.A. (ES) | 1977-04-12 | — | — | US | claimed |
| US-4017502-A | Process for purifying the mixed ester, ethylene glycol 1-(2-p-chlorophenoxy)-2-methylpropionate nicotinate | ALTER, S.A. (ES) | 1977-04-12 | — | — | US | disclosed |