Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.65 |
| ▸ | BCHE | P06276 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358693 | 0.85 | ACHE (0.71) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL5933261 | 0.85 | ACHE (0.71) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL11055153 | 0.83 | ACHE (0.68) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL10815679 | 0.82 | ACHE (0.61) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL10615391 | 0.81 | CYP3A4 (0.58) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL30519844 | 0.81 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL5933894 | 0.81 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL11793697 | 0.81 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4ENPC1 | |
| SCHEMBL11509302 | 0.80 | ACHE (0.64) | ACHEBCHEALDH1A1 | |
| SCHEMBL12043569 | 0.80 | ACHE (0.97) | ACHEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |