Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720518 | 0.80 | EPHX2 (0.61) | L3MBTL1SMN1; SMN2HTTKDM4EMAPT | |
| SCHEMBL21177412 | 0.77 | MEN1 (0.53) | L3MBTL1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL21177415 | 0.77 | MEN1 (0.53) | L3MBTL1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL30514831 | 0.77 | MEN1 (0.53) | L3MBTL1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL11717787 | 0.74 | LMNA (0.51) | L3MBTL1HTTKDM4EGAAMAPT | |
| SCHEMBL11720348 | 0.73 | ALDH1A1 (0.51) | L3MBTL1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11717344 | 0.72 | EPHX2 (0.47) | L3MBTL1MAPTKMT2AMEN1EPHX2 | |
| SCHEMBL4391929 | 0.72 | MAPT (0.71) | L3MBTL1SMN1; SMN2HTTKDM4EMAPT | |
| SCHEMBL21177419 | 0.72 | HPGD (0.50) | L3MBTL1SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL21177416 | 0.72 | HPGD (0.50) | L3MBTL1SMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065291-A | Herbicidal 1-(2-hydroxymethylpyrrolidinyl) carboxanilides | CHEVRON RESEARCH COMPANY (US) | 1977-12-27 | — | — | US | disclosed |