Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17419290 | 0.80 | ELANE (0.59) | ELANEHSD17B10KMT2AMEN1MAPT | |
| SCHEMBL9820463 | 0.80 | ELANE (0.59) | ELANEHSD17B10KMT2AMEN1MAPT | |
| SCHEMBL6648182 | 0.79 | MTNR1A (0.44) | HSD17B10KMT2AMEN1MAPTGAA | |
| SCHEMBL5072835 | 0.79 | MTNR1A (0.44) | HSD17B10KMT2AMEN1MAPTGAA | |
| SCHEMBL388144 | 0.79 | MTNR1A (0.44) | HSD17B10KMT2AMEN1MAPTGAA | |
| Hydrochloric Acid SCHEMBL9820527 | 0.78 | ELANE (0.58) | ELANEHSD17B10KMT2AMEN1MAPT | |
| SCHEMBL387761 | 0.78 | MTNR1A (0.43) | HSD17B10KMT2AMEN1MAPTGAA | |
| SCHEMBL10426746 | 0.77 | TSHR (0.62) | MAPTGAAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL4022213 | 0.75 | KMT2A (0.41) | KMT2AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28861868 | 0.75 | ELANE (0.53) | ELANEHSD17B10KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038414-A | ANTIARRHYTHMIA AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4014920-A | N-cinnamylcarbamic acid esters | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |