Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072835 | 0.80 | MTNR1A (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL388144 | 0.80 | MTNR1A (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL6648182 | 0.80 | MTNR1A (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL387761 | 0.79 | MTNR1A (0.43) | KMT2AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9010720 | 0.75 | MAPK1 (0.56) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL11719081 | 0.75 | ELANE (0.53) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL19449792 | 0.74 | EPHX2 (0.41) | KMT2AEPHX2ALDH1A1LMNAHDAC1 | |
| SCHEMBL11055560 | 0.73 | CA12 (0.48) | KMT2AALDH1A1LMNAHDAC1HDAC6 | |
| SCHEMBL2959585 | 0.72 | PDPK1 (0.43) | EPHX2ALDH1A1HDAC1PPARGPPARA | |
| SCHEMBL12168641 | 0.72 | PPARG (0.43) | KMT2AEPHX2ALDH1A1LMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945621-B1 | PROCESS TO PREPARE AMINO ACID DERIVATIVES | REDDY S LAB EU LTD DR (GB) | 2009-04-15 | — | — | EP | disclosed |