Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.58 |
| ▸ | ACHE | P22303 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717604 | 0.96 | BCHE (0.59) | BCHEACHEMAOBHRH3CYP1A2 | |
| SCHEMBL11716908 | 0.92 | SIGMAR1 (0.56) | BCHEACHEMAOBHRH3CYP1A2 | |
| SCHEMBL11715650 | 0.91 | BCHE (0.53) | BCHEACHEMAOB | |
| SCHEMBL11714059 | 0.91 | THRA (0.57) | BCHEACHECYP1A2CYP2D6SCN1A | |
| SCHEMBL11717402 | 0.89 | ESR1 (0.54) | BCHEACHEMAOB | |
| SCHEMBL11718751 | 0.88 | BCHE (0.52) | BCHEACHECYP1A2CYP2D6SCN1A | |
| SCHEMBL11712203 | 0.88 | THRA (0.55) | BCHEACHECYP1A2CYP2D6SCN1A | |
| SCHEMBL11719155 | 0.87 | KDM4E (0.52) | BCHEACHE | |
| SCHEMBL11719732 | 0.86 | THRA (0.54) | BCHEACHEHRH3CYP1A2CYP2D6 | |
| SCHEMBL11720978 | 0.85 | ESR1 (0.58) | BCHEACHEMAOBHRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |