Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722959 | 0.87 | KMT2A (0.79) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL18410446 | 0.82 | GLA (0.72) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL11722711 | 0.81 | RAB9A (0.74) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL4421308 | 0.81 | NPC1 (0.79) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL15599963 | 0.75 | GLA (0.78) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL353474 | 0.74 | — | — | |
| SCHEMBL20476296 | 0.74 | KMT2A (0.53) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL7362697 | 0.73 | POLB (0.67) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL2520746 | 0.72 | TP53 (0.62) | KMT2ANPC1RAB9AMEN1GLA | |
| SCHEMBL13210699 | 0.72 | KMT2A (0.73) | KMT2ANPC1RAB9AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026902-A | ANTIDIABETIC | KYORIN PHARMACEUTICAL CO., LTD. (JA) | 1977-05-31 | — | — | US | claimed |
| US-4026902-A | ANTIDIABETIC | KYORIN PHARMACEUTICAL CO., LTD. (JA) | 1977-05-31 | — | — | US | disclosed |