Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 4/20 | 0.37 |
| ▸ | SELE | P16581 | 4/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12881275 | 1.00 | ICAM1 (0.37) | ICAM1SELEVCAM1CYP11B1APP | |
| SCHEMBL1171911 | 0.98 | CYP11B1 (0.37) | ICAM1SELEVCAM1CYP11B1KDM4E | |
| SCHEMBL744790 | 0.82 | CYP11B1 (0.42) | CYP11B1GRM2CHRNB2CHRNA4MMP2 | |
| SCHEMBL29545943 | 0.82 | CYP11B1 (0.42) | CYP11B1GRM2CHRNB2CHRNA4MMP2 | |
| SCHEMBL14787991 | 0.80 | ICAM1 (0.35) | ICAM1SELEVCAM1APPL3MBTL1 | |
| SCHEMBL2455016 | 0.79 | CYP11B1 (0.40) | CYP11B1L3MBTL1GRM2CHRNB2CHRNA4 | |
| SCHEMBL15602862 | 0.78 | IDO1 (0.48) | APPKDM4EGLAL3MBTL1 | |
| SCHEMBL2233337 | 0.78 | GABRP (0.42) | ICAM1SELEVCAM1PIK3CDPIK3CA | |
| SCHEMBL2233332 | 0.78 | ICAM1 (0.36) | ICAM1SELEVCAM1APPL3MBTL1 | |
| SCHEMBL3405892 | 0.78 | ALDH1A1 (0.48) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507531-B2 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer | Sessler, Jonathan L. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20110034431-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | Sessler, Jonathan L. (US) | 2011-02-10 | — | — | US | disclosed |
| US-7838536-B2 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer | Sessler, Jonathan L. (US) | 2010-11-23 | — | — | US | disclosed |
| US-20090209509-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | Sessler, Jonathan L. (US) | 2009-08-20 | — | — | US | disclosed |
| US-7528125-B2 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer | Sessler, Jonathan L. (US) | 2009-05-05 | — | — | US | disclosed |
| WO-2007109290-A2 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | PHARMACYCLICS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| US-20070219276-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | PHARMACYCLICS, INC (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219276-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | SLC39A11, SLC39A3, SLC30A6 | ICAM1 2609/4885SELE 2904/4885VCAM1 2298/4885 |
| US-20110034431-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | SLC39A11, SLC39A3, SLC30A6 | ICAM1 2609/4885SELE 2904/4885VCAM1 2298/4885 |
| US-20090209509-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | SLC39A11, SLC39A3, SLC30A6 | ICAM1 2609/4885SELE 2904/4885VCAM1 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.