Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625367 | 0.85 | ALDH1A1 (0.41) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL8470461 | 0.85 | NAAA (0.31) | NAAAHIF1A | |
| SCHEMBL10916004 | 0.85 | ELANE (0.33) | ALDH1A1TSHR | |
| SCHEMBL20593347 | 0.83 | ALDH1A1 (0.39) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL22490553 | 0.83 | ALDH1A1 (0.39) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL20593400 | 0.83 | ALDH1A1 (0.39) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL10010765 | 0.83 | CA1 (0.34) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL8425136 | 0.78 | CA1 (0.31) | NAAA | |
| SCHEMBL9382913 | 0.77 | CA1 (0.44) | NAAA | |
| SCHEMBL10881640 | 0.76 | ALDH1A1 (0.36) | NAAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3161528-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | ESSILOR INT (FR) | 2020-03-04 | — | — | EP | disclosed |
| US-10370520-B2 | Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive | ESSILOR INTERNATIONAL (FR) | 2019-08-06 | — | — | US | disclosed |
| US-20170121498-A1 | Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive | ESSILOR INTERNATIONAL (FR) | 2017-05-04 | — | — | US | disclosed |
| EP-3161528-A1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | Essilor International (Compagnie Générale D'Optique) (FR) | 2017-05-03 | — | — | EP | disclosed |
| EP-2960687-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | ESSILOR INT (FR) | 2016-09-21 | — | — | EP | disclosed |
| EP-2960687-A1 | Composition for the manufacture of an ophtalmic lens comprising an uv-absorber and an anti-yellowing additive | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2015-12-30 | — | — | EP | disclosed |
| US-4001181-A | ACTINIC RADIATION STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |