SCHEMBL11720146

SCHEMBL11720146

CCN(CC)CCCCOc1ccc(Oc2ccc(N)c(N)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.49
MAOA P21397 1/20 0.49
NR4A1 P22736 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11709795 0.96 KDM4E (0.52) MAOBMAOANR4A1KDM4E
SCHEMBL11715546 0.91 NR4A1 (0.52) MAOBNR4A1KDM4E
SCHEMBL11715542 0.90 MAOA (0.50) MAOBMAOANR4A1
SCHEMBL11713366 0.90 LTA4H (0.49) MAOBMAOANR4A1
SCHEMBL4983140 0.86 KDM4E (0.62) MAOBMAOAKDM4E
SCHEMBL11717661 0.86 NR4A1 (0.49) MAOBMAOANR4A1
SCHEMBL11712870 0.86 LTA4H (0.49) NR4A1
SCHEMBL11711940 0.85 KDM4E (0.57) MAOBMAOANR4A1KDM4E
SCHEMBL11712896 0.84 LTA4H (0.47) NR4A1
SCHEMBL11822698 0.83 NR4A1 (0.61) NR4A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4010272-A ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-01 US disclosed