Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727674 | 0.95 | HRH3 (0.56) | HRH3KCNH2S1PR1PTGDR2FFAR4 | |
| SCHEMBL28718951 | 0.94 | HRH3 (0.55) | HRH3KCNH2S1PR1PTGDR2FFAR4 | |
| SCHEMBL25366257 | 0.92 | S1PR1 (0.57) | HRH3KCNH2S1PR1FFAR4RAB9A | |
| SCHEMBL9808038 | 0.84 | HRH3 (0.71) | HRH3KCNH2CYP3A4CYP2C9 | |
| SCHEMBL11724117 | 0.83 | MEN1 (0.53) | PTGDR2FFAR4MEN1KMT2ANPC1 | |
| SCHEMBL5274797 | 0.83 | MEN1 (0.70) | HRH3KCNH2PTGDR2MEN1KMT2A | |
| SCHEMBL5326805 | 0.81 | MEN1 (0.67) | HRH3PTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL31448501 | 0.80 | PPARA (0.65) | FFAR4PPARA | |
| SCHEMBL27508210 | 0.80 | HRH3 (0.61) | HRH3KCNH2MEN1KMT2ANPC1 | |
| SCHEMBL4333330 | 0.79 | HRH3 (0.60) | HRH3KCNH2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013708-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | claimed |
| US-4013708-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |