SCHEMBL11720920

SCHEMBL11720920

COC(=O)C1=C(c2ccccc2)C(c2ccccc2)=C(C(=O)OC)C1=O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 7/20 0.75
FGFR2 P21802 7/20 0.75
FGFR4 P22455 7/20 0.75
FGFR3 P22607 7/20 0.75
SRC P12931 4/20 0.75
PDE4B Q07343 1/20 0.52
TSHR P16473 1/20 0.50
HSP90AA1 P07900 3/20 0.47
HSP90AB1 P08238 2/20 0.47
ALDH1A1 P00352 3/20 0.46
HTT P42858 3/20 0.46
MAPT P10636 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
MITF O75030 1/20 0.46
PPARG P37231 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969780 0.86 FGFR1 (0.88) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL143675 0.86 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL8359086 0.80 PPARG (0.63) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL10653666 0.79 FGFR1 (0.54) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL3578768 0.78 FGFR1 (0.74) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL145725 0.78 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL144476 0.78 FGFR1 (0.74) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL147746 0.78 FGFR1 (0.74) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL143878 0.77 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL10239348 0.77 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170368015-A1 NOVEL COMPOUND AND ANTIVIRAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) 2017-12-28 US disclosed
US-4011378-A AROMATIZED POLYACETYLENES GENERAL ELECTRIC COMPANY (US) 1977-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170368015-A1 NOVEL COMPOUND AND ANTIVIRAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT SARS1, ZC3HAV1, ZC3HAV1L FGFR1 899/4885FGFR2 2531/4885FGFR4 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.