SCHEMBL8359086

SCHEMBL8359086

CCOC(=O)C1=C(c2ccccc2)C(c2ccccc2)=C(C(=O)OCC)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.63
ALDH1A1 P00352 3/20 0.59
LMNA P02545 3/20 0.59
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPSR1 Q6W5P4 3/20 0.59
KDM4E B2RXH2 2/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
TP53 P04637 1/20 0.59
HSP90AA1 P07900 1/20 0.59
MAPK1 P28482 1/20 0.59
MPI P34949 1/20 0.59
HKDC1 Q2TB90 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538581 0.87 PPARG (0.72) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL17969781 0.87 ALDH1A1 (0.78) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL28509371 0.87 PPARG (0.56) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL14000243 0.84 PPARG (0.53) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL8361087 0.83 KDM4E (0.53) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL3576647 0.81 PPARG (0.76) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL3570952 0.80 PPARG (0.74) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL10648370 0.80 KDM4E (0.51) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL11720920 0.80 FGFR1 (0.75) PPARGALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL9904567 0.79 MAPT (0.78) PPARGALDH1A1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457475-A Method for preparing modified PEF copolyester by using citric acid-based aromatic diester 天津理工大学 2021-03-09 CN claimed
CN-112266470-A Preparation of bio-based aromatic monomer and preparation method of related homopolyester and copolyester 天津理工大学 2021-01-26 CN claimed
CN-112457475-A Method for preparing modified PEF copolyester by using citric acid-based aromatic diester 天津理工大学 2021-03-09 CN disclosed
CN-112266470-A Preparation of bio-based aromatic monomer and preparation method of related homopolyester and copolyester 天津理工大学 2021-01-26 CN disclosed
CN-112266470-A Preparation of bio-based aromatic monomer and preparation method of related homopolyester and copolyester 天津理工大学 2021-01-26 CN disclosed
US-5945502-A Electroluminescent polymer compositions and processes thereof XEROX CORPORATION (US) 1999-08-31 US disclosed