SCHEMBL17969780

SCHEMBL17969780

COC(=O)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 8/20 0.88
▸ FGFR2 P21802 8/20 0.88
▸ FGFR4 P22455 8/20 0.88
▸ FGFR3 P22607 8/20 0.88
▸ SRC P12931 5/20 0.88
▸ HSP90AA1 P07900 7/20 0.68
▸ HSP90AB1 P08238 5/20 0.68
▸ NPSR1 Q6W5P4 4/20 0.61
▸ LMNA P02545 4/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ MEN1 O00255 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ HKDC1 Q2TB90 2/20 0.61
▸ L3MBTL1 Q9Y468 2/20 0.61
▸ XBP1 P17861 2/20 0.61
▸ MAPT P10636 4/20 0.58
▸ HTT P42858 3/20 0.58
▸ TDP1 Q9NUW8 3/20 0.58
▸ KDM4E B2RXH2 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143675 0.93 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL11720920 0.86 FGFR1 (0.75) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL17973999 0.84 HSP90AA1 (0.64) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL17969775 0.83 HSP90AA1 (0.62) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL17969781 0.83 ALDH1A1 (0.78) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL147746 0.82 FGFR1 (0.74) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL12382276 0.82 HSP90AA1 (0.61) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL147378 0.81 FGFR1 (0.72) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL143878 0.81 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL17969802 0.81 HSP90AA1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 — — EP disclosed
Send feedback