Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NGFR | P08138 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723446 | 0.85 | GPR35 (0.68) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL11638566 | 0.85 | GLA (0.58) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL11643204 | 0.85 | GPR35 (0.68) | GLAGAAGPR35CYP1A2NGFR | |
| SCHEMBL11725265 | 0.84 | GLA (0.57) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL11639956 | 0.84 | GLA (0.57) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL11720192 | 0.80 | GLA (0.53) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL11807432 | 0.80 | GLA (0.68) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL4987172 | 0.79 | GLA (0.56) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL2903161 | 0.75 | GLA (0.51) | GLAGAAGPR35CYP1A2XDH | |
| SCHEMBL4993673 | 0.75 | GLA (0.51) | GLAGAAGPR35CYP1A2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064248-A | TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1977-12-20 | — | — | US | disclosed |