Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | NGFR | P08138 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721616 | 0.85 | GLA (0.61) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11641819 | 0.81 | GPR35 (1.00) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11638544 | 0.79 | GPR35 (0.71) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL4990158 | 0.78 | GPR35 (0.56) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11638708 | 0.77 | GPR35 (0.69) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11640479 | 0.77 | GPR35 (0.69) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL3335123 | 0.75 | KDM4E (0.67) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL30054313 | 0.75 | GAA (0.77) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11641823 | 0.73 | GPR35 (0.63) | GPR35KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL11810085 | 0.73 | GPR35 (0.70) | GPR35KDM4EHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4064248-A | TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |