Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722566 | 0.80 | PTGS1 (0.50) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| SCHEMBL11722981 | 0.77 | ADRB3 (0.43) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| SCHEMBL11714841 | 0.76 | ADRB2 (0.47) | CYP2D6ADRB2ADRB1ADRB3OPRK1 | |
| SCHEMBL11716903 | 0.76 | ADRB2 (0.50) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL20369160 | 0.73 | PTGS1 (0.55) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| SCHEMBL31126368 | 0.73 | PTGS1 (0.68) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| SCHEMBL5317103 | 0.73 | PTGS1 (0.68) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| Hydrochloric Acid SCHEMBL31111430 | 0.72 | MAPT (0.68) | PTGS1SLC6A2CYP2D6MAPTADRB2 | |
| SCHEMBL13148928 | 0.71 | ADRB2 (0.71) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL11719579 | 0.71 | ADRB2 (0.64) | PTGS1SLC6A2CYP2D6MAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014920-A | N-cinnamylcarbamic acid esters | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |