Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317103 | 1.00 | PTGS1 (0.68) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL31111430 | 0.99 | MAPT (0.68) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL28412321 | 0.83 | PTGS1 (0.74) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL10694902 | 0.82 | ALDH1A1 (0.62) | MAPTCYP1A2KMT2ALMNAKDM4E | |
| SCHEMBL7946116 | 0.81 | PTGS1 (0.77) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| Prenalterol SCHEMBL249753 | 0.81 | PTGS1 (1.00) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| Prenalterol SCHEMBL10816429 | 0.81 | PTGS1 (1.00) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL22639751 | 0.81 | PTGS1 (0.77) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| Prenalterol SCHEMBL10788435 | 0.81 | PTGS1 (1.00) | PTGS1SLC6A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL10551178 | 0.81 | ADRB2 (0.67) | CYP2D6ADRB2ADRB1ADRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118655253-B | Disposable detection method for bisoprolol hydrochlorothiazide tablet related substances | 北京华素制药股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118655253-A | Disposable detection method for bisoprolol hydrochlorothiazide tablet related substances | 北京华素制药股份有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118655253-B | Disposable detection method for bisoprolol hydrochlorothiazide tablet related substances | 北京华素制药股份有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118655253-A | Disposable detection method for bisoprolol hydrochlorothiazide tablet related substances | 北京华素制药股份有限公司 | 2024-09-17 | — | — | CN | disclosed |